AA · United States · updated 2026-06-01

American Airlines medication liquid rules

Essential liquid medicines are exempt from the 100 ml rule on American Airlines flights. You can carry more than 100 ml in hand luggage if you have supporting documentation — usually a prescription or a doctor's letter — and declare it at the security checkpoint.

Send these rules to whoever you're travelling with.

What to know before you pack

American Airlines cabin bag at a glance

Personal item: 45 × 35 × 20 cm

Overhead bag: 56 × 36 × 23 cm

Full American Airlines hand luggage rules

Frequently asked

Do I need a prescription for liquid medicine on American Airlines?

For quantities over 100 ml, bring a prescription or doctor's letter. Under 100 ml, medicine can simply go in your clear liquid bag with no paperwork.

Where should medication go on a American Airlines flight?

In your cabin bag, within easy reach. Medicines you may need during the flight should never be checked into the hold.

More American Airlines liquid topics

Sources