Quick answer
Medically necessary liquids are exempt from the 100ml cabin rule in every major jurisdiction — US (TSA), UK (DfT), EU (EC 185/2010), Canada (CATSA) and Australia. You do not need to fit them in the 1-litre clear bag. Take "a reasonable quantity for the trip", declare them at the start of screening, and expect them to be inspected separately.
Country-by-country liquid medication rules
| Country / region | Over 100ml allowed? | Paperwork expected | Screening notes |
|---|---|---|---|
| United States (TSA) | Yes — reasonable quantity | Not required, but recommended | Declare at start. Bottles may be opened for vapour or strip testing. |
| United Kingdom (DfT) | Yes — essential medicine | Prescription or doctor's letter for >100ml liquid meds | Show to security officer. Some airports require a supporting letter for controlled drugs. |
| European Union | Yes — essential medicine | Prescription or medical certificate recommended | EC 185/2010 exempts medicines needed during the trip. Enforcement varies by country. |
| Canada (CATSA) | Yes — reasonable quantity | Not required for OTC; prescription helpful | Present separately at pre-board screening. |
| Australia | Yes — quantity for the flight + a bit extra | Doctor's letter for injectables and controlled substances | Domestic and international rules match. Powdered meds >350g face extra screening on US-bound flights. |
| UAE / Dubai | Yes, but stricter on controlled substances | Prescription mandatory for many common medicines (e.g. codeine, tramadol) | Check the UAE Ministry of Health controlled-drug list before travelling. |
| Singapore | Yes — declare on arrival | Prescription required for controlled substances | Some common Western OTC ingredients (e.g. pseudoephedrine) are restricted. |
| Japan | Yes — Yakkan Shoumei for >1 month supply | Yakkan Shoumei import certificate for larger quantities and some ingredients | Stimulant-containing meds (some ADHD meds, Adderall) are banned outright. |
What counts as "medically necessary liquid"
- Prescription liquids (cough syrups, liquid antibiotics, methadone)
- Insulin, injectable medication and pre-filled syringes
- Inhalers, nebuliser solution and asthma medication
- EpiPens and other emergency auto-injectors
- Eye drops, ear drops and contact lens solution
- Liquid nutrition prescribed by a doctor (e.g. for feeding tubes)
- Cooling gel packs used to keep medication at required temperature
- Baby formula, breast milk and baby food (see our dedicated guide)
The exact steps at the checkpoint
- Take medication out of your bag before it reaches the X-ray belt.
- Tell the officer at the start of screening: "I have medication over 100ml."
- Put medicines in a separate tray. Do NOT put them in your 1-litre clear bag — the exemption means they don't count toward it.
- Expect additional inspection: visual check, vapour test, or (rarely) opening the bottle. You can refuse opening; you'll receive additional pat-down screening instead.
- If you carry a cooling gel pack, it can travel frozen or partially frozen — declare it too.
Controlled and restricted medicines
Some medicines legal at home are controlled or banned in your destination country. The most common surprises: Adderall and other amphetamine-based ADHD medication are banned in Japan; codeine, tramadol and diazepam are controlled in the UAE and Singapore; some cold and flu medicines containing pseudoephedrine are restricted in Japan and Mexico. Check the destination country's official controlled substances list before you fly and carry a doctor's letter naming the medication, dose and reason.
Cabin vs checked bag: where to pack medication
Always carry essential medication in your cabin bag. Checked luggage can be delayed, lost or exposed to freezing temperatures in the hold. If you're carrying a large supply, split it: enough for the trip plus a few days in the cabin, spare supply in checked. Keep prescriptions in your cabin bag with the medication itself.
Powdered medication and injectables
On US-bound international flights, powders over 350ml (about 12oz) must be removed from your bag for separate screening and may need to be tested. Prescription powdered medicines are exempt but declaring them speeds things up. Injectables travel fine — carry the labelled packaging or a doctor's note explaining why you need needles in the cabin.
Traveller checklist
- Original labelled packaging for every liquid medicine
- Copy of prescription or doctor's letter (paper or PDF on your phone)
- For controlled substances: a letter naming the drug, dose and prescribing doctor
- Small cool bag or gel pack if the medication needs to stay cool
- A photo of each medication label as a backup if packaging is damaged
- For international trips: check destination-country restrictions at least 2 weeks before flying